ƒPublications„

1)A. G. Dias, K. Tsuru, S. Hayakawa, M. A. Lopes, J. D. Santos, A. Osaka, "Crystallization studies of biodegradable CaO-P2O5 glass with MgO and TiO2 for bone regeneration applications", Glass Technology, 45, 78-79 (2004).

2) S. Takemoto, Y. Kusudo, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Selective protein adsorption and blood compatibility of hydroxyl-carbonate apatites", Journal of Biomedical Materials Research, 69A[3], 544-551 (2004).

3)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "In vitro platelet adhesion and protein adsorption of biomedical implant modified with polysaccharide", Transaction of the Materials Research Society of Japan, 29[6], 2671-2674 (2004).

4)N. Azuma, T. Ikoma*, A. Osaka, J. Tanaka* (*BMC-NIMS), "Novel hydrogels with zinc and L(-)-malic acid ; their synthesis and characterizations", Journal of Non-Crystalline Solids, 342[1-3], 125-131 (2004).

5)S. Takemoto, T. Yamamoto, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Platelet adhesion on titanium oxide gels: effects of surface oxidation", Biomaterials, 25[17], 3485-3492 (2004).

6)Y-X. Liu, K. Tsuru, S. Hayakawa, A. Osaka, "In vitro bioactive nano-crystalline TiO2 layers grown at glass-coating/titanium interface", Journal of the Ceramics Society of Japan, 112[8], 452-457 (2004).

7)J-M. Wu, K. Tsuru, S. Hayakawa, A. Osaka, "Low-temperature preparation of anatase and rutile layer on titanium substrate and their ability to induce in vitro apatite deposition", Journal of the American Ceramics Society, 87[9], 1635-1642 (2004).

8)Y-X. Liu, K. Tsuru, S. Hayakawa, A. Osaka, "Topotaxial nucleation and growth of TiO2 submicron-scale rod arrays on titanium Substrates via Sodium Tetraborate Glass Coating", Journal of the Ceramics Society of Japan, 112[10], 567-571 (2004).

9)T. Yabuta, K. Tsuru, S. Hayakawa, A. Osaka, "Synthesis of blood compatible PDMS-based organic-inorganic hybrid coatings", Journal of Sol-Gel Science and Technology, 31[1-3], 273-276 (2004).

10)K. Tsuru, S. Hayakawa, A. Osaka, "Synthesis of bioactive and porous organic-inorganic hybrids for biomedical applications", Journal of Sol-Gel Science and Technology, 32[1-3], 201-205 (2004).

11)N. Azuma, T. Ikoma*, A. Osaka, J. Tanaka* (*BMC-NIMS), "Effects of hyaluronic acid on the rheological properties of zinc-carboxylate hydrogels", Materials Science & Engineering C, 24[6-8], 703-707 (2004).

12)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "Preparation of organotitanium molecular layers for biomedical applications", Materials Science & Engineering C, 24[6-8], 901-905 (2004).

13)Y-X. Liu, K. Tsuru, S. Hayakawa, A. Osaka, "Potassium titanate nanorod arrays grown on titanium substrates and their in vitro bioactivity", Journal of the Ceramics Society of Japan, 112[12], 634-640 (2004).

14)A. Osaka, K. Tsuru, S. Hayakawa, "Titania derived from combined chemical and thermal treatments of titanium: In vitro apatite forming ability", Phosphorous Res. Bulletin, 17, 130-141 (2004).

ƒProceedings„

1)K. Tsuru, Y. Yamane, T. Yamamoto, S. Hayakawa, A. Osaka, "Blood compatibility of sol-gel derived metal oxide layers -in vitro evaluation", Proceedings of International Symposium on Bio-Inspired System (ISBS2004), WBEB2004-16, pp. 70-71, (2004).

2)T. Shozui, S. Kawasaki, K. Tsuru, S. Hayakawa, A. Osaka, "In vitro apatite-forming ability of titania films derived from chemical treatment of titanium with hydrogen peroxide solution", Archives of BioCeramics Research, Vol. 4, pp. 175-179 (2004).

3)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, M. A. Lopes, J. D. Santos, M. H. Fernandes, "In Vitro biological reactivity of porous chitosan-organosiloxane hybrids", Proceedings of XX International Congress on Glass (ICG), O-12-010 (2004).

4)K. Tsuru, T. Yabuta, M. Nagahara, S. Hayakawa, A. Osaka, K. Kataoka, N-H. Huh, "Preparation of porous TEOS-PDMS hybrids and their apprication for cell culture matrix", Proceedings of XX International Congress on Glass (ICG), O-12-017 (2004).

5)Y-X. Liu, K. Okamoto, S. Hayakawa, K. Tsuru, A. Osaka, "Preparation of titania nano-rod array on titanium substrates by microflux method", Proceedings of XX International Congress on Glass (ICG), O-16-022 (2004).

6)Y. Yamane, K. Tsuru, S. Hayakawa, A. Osaka, "Platelet adhesion on sol-gel derived metal oxide films", Proceedings of the 21th International Japan-Korea Seminar on Ceramics, pp. 101-105 (2004).

7)S. Nagai, K. Tsuru, S. Hayakawa, A. Osaka, "Conformational change of protein due to contact with bioceramic materials", Bioceramics, vol.17, pp. 517-520 (2004).

8)A. Osaka, T. Yoshioka, T. Yabuta, K. Tsuru, S. Hayakawa, "Blood compatibility of organic-inorganic biomedical materials", Bioceramics, vol.17, pp. 713-716 (2004).

9)K. Tsuru, Y. Shirosaki, S. Hayakawa, A. Osaka, M. A. Lopes*, J. D. Santos, M. H. Fernandes, "In vitro biodegradability of chitosan-organosiloxane hybrid membrane", Bioceramics, vol.17, pp. 823-826 (2004).

ƒInternational Congress„

1)K. Tsuru, Y. Yamane, T. Yamamoto, S. Hayakawa, A. Osaka, "Blood Compatibility of Sol-gel Derived Metal Oxide Layers -In Vitro Evaluation", International Symposium on Bio-Inspired System (ISBS2004), WBEB2004-16, pp.70-71, 2004.1.24, Kitakyushu, Japan.

2)Y. Liu, K. Okamoto, S. Hayakawa, K. Tsuru, A. Osaka, "Preparation of Titanate Nano-Rod Array on Titanium Substrates by Novel Microflux Method", 106th Annual Meeting & Exposition of The American Ceramic Society, AM-S6-5-2004, p. 50, 2004.4.18~21, Indianapolis, Indiana, USA.

3)J-F. Liu, S. Hayakawa, K. Tsuru, A. Osaka, "Hydroxyapatite Formation On and Inside of Cotton Fibrilla with an Oxysulfate Solution", 7th World Biomaterials Congress, THU2.032 2004.5.17-21, Sydney, Australia.

4)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "Protein Adsorption Properties of Stainless-steel and Titanium Modified with Alginic Acid", 7th World Biomaterials Congress, THU1.004, 2004.5.17-21, Sydney, Australia.

5)N. Azuma, T. Ikoma*, A. Osaka, J. Tanaka* (*BMC-NIMS), "Effects of Hyaluronic Acid on the Rheology of Zinc/malic Acid Hydrogels", 7th World Biomaterials Congress, THU1.093, 2004.5.17-21, Sydney, Australia.

6)T. Shozui, S. Kawasaki, K. Tsuru, S. Hayakawa, A. Osaka, "In Vitro Apatite-forming Ability of Titania Films Derived from Chemical Treatment of Titanium with Hydrogen Peroxide Solution", Asian BioCeramicsCP-12, pp. 175-179, 2004.9.6-8, Kongju, Korea.

7)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, M. A. Lopes, J. D. Santos, M. H. Fernandes, "In Vitro Biological Reactivity of Porous Chitosan-organosiloxane Hybrids", XX International Congress of Glass (ICG), Abstract O-12-010 p.230, 2004.9.27, Kyoto, Japan.

8)K. Tsuru, T. Yabuta, M. Nagahara, S. Hayakawa, A. Osaka, K. Kataoka, N-H. Huh, "Preparation of Porous TEOS-PDMS Hybrids and Their Apprication for Cell Culture Matrix", XX International Congress of Glass (ICG), Abstract O-12-017 p.234, 2004.9.27, Kyoto, Japan.

9)Y. Liu, K. Okamoto, S. Hayakawa, K. Tsuru, A. Osaka, "Preparation of Titania Nano-rod Array on Titanium Substrates by Microflux Method", XX International Congress of Glass (ICG), Abstract O-16-022 p.296, 2004.9.30, Kyoto, Japan.

10)A. Osaka, T. Shozui, T. Yoshioka, S. Hayakawa, K. Tsuru, "Preparation and Cell Response of Organic-Inorganic Hybrids", Biomaterialien, vol. 5, no. 3, Abstracts, p.188, 2004.10.7-9, Berlin, Germany.

11)Y. Yamane, K. Tsuru, S. Hayakawa, A. Osaka, "Platelet Adhesion on Sol-gel Derived Metal Oxide Films", The 21th International Korea-Japan Seminar on Ceramics, pp. 101-105, 2004.11.4-6, Gwangju, Korea.

12)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, M. A. Lopes, J. D. Santos, M. H. Fernandes, "Chitosan-Organosiloxane Hybrids of Scaffolds for Tissue Engineering", 4th Asian International Symposium on Biomaterials (AISB4), AISB-P-007, p.162, 2004.11.18, Tsukuba, Japan.

13)K. Tsuru, T. Shozui, T. Yoshioka, S. Hayakawa, A. Osaka, "In Vitro Blood Compatibility of Metal Implants Hybridized With Organic or Inorganic Materials", 4th Asian International Symposium on Biomaterials (AISB4), AISB-P-072, p.251, 2004.11.18, Tsukuba, Japan.

14)N. Azuma, T. Ikoma*, A. Osaka, J. Tanaka* (*BMC-NIMS), "Control of Denaturation Temperatures of Type-I Collagen Extracted from Fish Scales", 4th Asian International Symposium on Biomaterials (AISB4), AISB-P-111, p.302, 2004.11.18, Tsukuba, Japan.

15)S. Hayakawa, Y. Liu, K. Okamoto, K. Tsuru, A. Osaka, "Formation of Titania Submicron-Scale Rod Arrays on Titanium Substrate and In Vitro Biocompatibility", Materials Research Society Fall Meeting, AA6.9, p. 634, 2004.11.29~12.3, Boston, USA.

16)S. Nagai, K. Tsuru, S. Hayakawa, A. Osaka, "Conformational Change of Protein due to Contact with Bioceramic Materials", The 17th International Symposium on Ceramics in Medicine, Bioceramics, Vol.17, pp. 517-520, 2004.12.8-12, New Orleans, USA.

17)A. Osaka, T. Yoshioka, T. Yabuta, K. Tsuru, S. Hayakawa, "Blood Compatibility of Organic-inorganic Biomedical Materials", The 17th International Symposium on Ceramics in Medicine, Bioceramics, Vol.17, pp. 713-716, 2004.12.8-12, New Orleans USA.

18)K. Tsuru, Y. Shirosaki, S. Hayakawa, A. Osaka, M. A. Lopes*, J. D. Santos*, M. H. Fernandes* (*ƒ|ƒ‹ƒg‘ĺ), "In Vitro Biodegradability of Chitosan-Organosiloxane Hybrid Membrane", The 17th International Symposium on Ceramics in Medicine, Bioceramics, Vol.17, pp. 823-826, 2004.12.8-12, New Orleans USA.