ƒPatents„

1)A. Osaka, S. Hayakawa, K. Tsuru, K. Koyano, K. Ohta, "Biocompatible titanium implant for medical use", US2002-0143398A1, 2002”N10ŒŽ3“ú


ƒBooksEReviews„

1)A. Osaka, S. Hayakawa, K. Tsuru, "Biomimetic Apatite Coating on Chemically and Electrochemically Treated Titanium", in Biomimetic Calcium Phosphate Coatings 2002, ed. Hai Bo Wen, Research Signpost, ISBN81-7736-090-6, pp. 1-13, 2002”N


ƒPublications„

1)X.-X. Wang, S. Hayakawa, K. Tsuru, A. Osaka, "Bioactive titania gel layers formed by chemical treatment of Ti substrate with a H2O2/HCl solution", Biomaterials, 23[5], 1353-1357 (2002).

2)J.-M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, "Crystallization of anatase from amorphous titania in hot water and in vitro biomineralization", Journal of The Ceramic Society of Japan, 110, 78-80 (2002).

3)J.-M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, "Nanocrystalline titania made from interactions of Ti with hydrogen peroxide solutions containing tantalum chloride", Crystal Growth&Design, 2[2], 147-149 (2002).

4)J.-M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, "Soft solution approach to prepare crystalline titania films", Scripta Materialia, 46[10], 705-709 (2002).

5)J.-M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, "Porous titania films prepared from interactions of titanium with hydrogen peroxide solution", Scripta Materialia, 46[1], 101-106 (2002).

6)Y. Aburatani, K. Tsuru, S. Hayakawa, A. Osaka, "Mechanical properties and microstructure of bioactive ORMISILs containing silica particles", Materials Science and Engineering C, 20[1-2], 195-198 (2002).

7)J.M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, "In vitro bioactivity of anatase film obtained by direct deposition from aqueous titanium tetrafluoride solutions", Thin Solid Films, 414[2], 275-280 (2002).

8)L. Ren, K. Tsuru, S. Hayakawa, A. Osaka, "Novel approach to fabricate porous gelatin-siloxane hybrids for bone tissue engineering", Biomaterials, 23[24], 4765-4773 (2002).


ƒProceedings„

1)S. Hayakawa, A. Osaka, "29Si NMR study of divalent metal oxyfluorosilicate glass", Physics and Chemistry of Glasses, Vol. 43C, Optical, opto-electronics, nano and coloured glasses, pp. 224-227 (2002).

2)K. Tsuru, S. Hayakawa, C. Ohtsuki, A. Osaka, "In vitro bioactivity and structure of alkali borosilicate glasses", Physics and Chemistry of Glasses, Vol. 43C, 326-329 (2002).

3)Y. Aburatani, K. Tsuru, S. Hayakawa, A. Osaka, "Heating effect on properties of organic-inorganic hybrids containing colloidal silica particles", Key Engineering and Materials, Vols. 218-220, 445-448 (2002).

4)S. Takashima, Y. Kusudo, S. Takemoto, K. Tsuru, S. Hayakawa, A. Osaka, "Synthesis of carbonate-hydroxy apatite and selective asorption activity against specific pathogenic substances", Key Engineering and Materials, Vols. 218-220, 175-220 (2002).

5)J-M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, X.-X. Wang, "In vitro evaluation on bone-bonding of chemically modified titanium", Key Engineering and Materials, Vols. 218-220, 141-144 (2002).

6)S. Hayakawa, K. Shibata, K. Tsuru, A. Osaka, "Apatite induction on titania due to combined chemical and thermal treatments of titanium", Key Engineering and Materials, Vols. 218-220, 71-74 (2002).

7)T. Yabuta, E.P. Bescher, J.D. Mackenzie, K. Tsuru, S. Hayakawa, A. Osaka, "Synthesis of bioactive porous organic-inorganic hybrid material for biomedical application", Proceedings of the International Symposium on Bio-integrated Materials and Tissue Engineerng, pp. 73-75 (2002).

8)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Apatite formation and cell adhesion on silicone surface modified with gamma-Methacryloxypropyltrimethoxysilane by emulsion polymerization", Proceedings of the International Symposium on Bio-integrated Materials and Tissue Engineerng, pp. 76-78 (2002).

9)N. Azuma, A. Osaka, T. Ikoma, J. Tanaka, "The formation of multiple quality hyaluronic acid materials cross-linked with Fe(III) ion and organic acid", Proceedings of the International Symposium on Bio-integrated Materials and Tissue Engineerng, pp. 86-87 (2002).

10)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "Surface characterization and platelet adhesion of alginic acid layers on glass substrates", Proceedings of 3rd Asian International Symposium on Biomaterials and Drug Delivery Systems, pp. 222-225 (2002).

11)A. Yamada, K. Tsuru, S. Hayakawa, A. Osaka, "Chitosan-organosiloxane hybrids for biomedical applications", Proceedings of 3rd Asian International Symposium on Biomaterials and Drug Delivery Systems, pp. 279-282 (2002).

12)K. Tsuru, Y. Higashi, S. Hayakawa, A. Osaka, "Effects of organic molecules in the Kokubo's simulated body fluid on apatite formation on glass and titanium substrates", Proceedings of the 2nd Asian BioCeramics Symposium (ABC2002), pp. 81-84 (2002).

13)E. Fujii, K. Kawabata, H. Yoshimatsu, A. Osaka, Y. Miura, "Development of calcia ceramics with high hydration resistance", Proceedings of the 19th Korea-Japan International Seminar on Ceramics, pp. 480-483 (2002).

14)S. Takemoto, T. Yamamoto, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Blood compatibility of titanium oxide gels on titanium substrates", Proceedings of the 19th Korea-Japan International Seminar on Ceramics, pp. 217-220 (2002).

15)K. Shibata, K. Tsuru, S. Hayakawa, A. Osaka, "Biomimetic apatite deposition on titanium substrates treated with low concentration H2O2 solutions", Bioceramics, Vol. 15, pp. 55-58 (2002).

16)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Cytocompatibility on silicone modified with organoalkoxysilane due to emulsion polymerization", Bioceramics, Vol. 15, pp. 687-690 (2002).

17)J.-M. Wu, K. Tsuru, S. Hayakawa, A. Osaka, "Low temperature deposition of bioactive crystalline titania films: Effects of tantalum", Bioceramics, Vol. 15, pp. 533-536 (2002).

18)F. Xiao, K. Tsuru, S. Hayakawa, A. Osaka, "Low temperature synthesis of bioactive titania thin films by two-step treatment", Bioceramics, Vol. 15, pp. 537-540 (2002).

19)Y. Aburatani, T. Uchida, Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, "Response to osteoblastic cell of the organic-inorganic hybrids", Bioceramics, Vol. 15, pp.683-686 (2002).

20)S. Takashima, T. Yamamoto, K. Tsuru, S. Hayakawa, A. Osaka, "Deactivation of active oxygen species due to metals and their blood compatibility", Bioceramics, Vol. 15, pp.105-108 (2002).


ƒInternational Congress„

1)Y. Kusudo, S. Takemoto, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Selective adsorption of proteins on hydroxy-carbonate apatite", The 40th Symposium on Basic Science of Ceramics International Symposium on New Wave of Ceramics for the 21st Century, Abstract 1C-12I, pp. 98-99, 2002.1.22, Osaka, Japan.

2)K. Tsuru, S. Takemoto, S. Hayakawa, A. Osaka, S. Takashima, "Platelet adhesion on oxidated titanium substrates", The 40th Symposium on Basic Science of Ceramics International Symposium on New Wave of Ceramics for the 21st Century, Abstract 1C-17I, pp. 108-109, 2002.1.22, Osaka, Japan.

3)A. Mori, N. Tomita, T. Kaneeda, K. Nagata, H. Moriya, A. Osaka, K. Kuramoto, "Wear resistence of UHMPWPE mixed with vitamin E supposing lift-off in TKA", The 48th Annual Meeting of the Orthopaedic Research Society, Poster, No. 1041111, Transactions p. 1041, 2002.2.10-12, Dallas, USA.

4)T. Yabuta, E.P. Bescher, J.D. Mackenzie, K. Tsuru, S. Hayakawa, A. Osaka, "Synthesis of bioactive porous organic-inorganic hybrid materials for biomedical application", The International Symposium on Bio-integrated Materials and Tissue Engineering, Abstract P-13, pp. 73-75, 2002.3.7, Tokyo, Japan.

5)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Apatite formation and cell adhesion on silicone surface modifed with gamma-methacryloxypropyltrimethoxysilane by emulsion polymerization", The International Symposium on Bio-integrated Materials and Tissue Engineering, Abstract P-14, pp. 76-78, 2002.3.7, Tokyo, Japan.

6)N. Azuma, A. Osaka, T. Ikoma, J. Tanaka, " The formation of mutiple quality hyaluronic acid materials cross-linked with Fe(II) ion and organic acid", The International Symposium on Bio-integrated Materials and Tissue Engineering, Abstract P-18, pp. 86-87, 2002.3.7, Tokyo, Japan.

7)K. Tsuru, M. Kubo, S. Hayakawa, A. Osaka, "Biomimetic apatite deposition on sol-gel derived silica gel", Materials Research Society Spring Meeting, Abstract N7.12, p.241, 2002.4.4, San Francisco, USA.

8)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "Surface characterization and platelet adhesion of aliginic acid layers on glass substrates", The 3rd Asian International Symposium on Biomaterials and Drug Delivery Systems, Abstract pp.222-225, 2002.4.15, Taipei, Taiwan.

9)A. Yamada, K. Tsuru, S. Hayakawa, A. Osaka, "Chitosan-organosiloxane hybrids for biomedical applications", The 3rd Asian International Symposium on Biomaterials and Drug Delivery Systems, Abstract pp.279-282, 2002.4.15, Taipei, Taiwan.

10)A. Mori, N. Tomita, I. Sakuramoto, A. Osaka, K. Kuramoto, "Mechanical behavior of Vitamin E-containing UHMWPE", The 28th Annual Meeting of Society for Biomaterials, Poster No. 618, p. 618, 2002.4.25-27, Tampa, USA.

11)J.M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, "Preparation of anatase and rutile layers on titanium substrates in aqueous solutions and their tissue-bonding ability", The American Ceramic Society, 104th Annual Meeting & Exposition, Abstract p. 80, 2002.4.30, Missouri, USA.

12)K. Tsuru, Y. Higashi, S. Hayakawa, A. Osaka, "Effects of organic molecules in the Kokubo's simulated body fluid on apatite formation on glass and titanium substrates", The 2nd Asian BioCeramics Symposium (ABC2002), Proceedings, pp. 81-84, 2002.10.25, Gteongju, Korea.

13)N. Azuma, T. Ikoma, H. Kobayashi, A. Osaka, J. Tanaka, " The formation of multiple pore quality hyaluronic acid materials cross-linked with Fe(III) ion and organic acid", Interational Symposium on Advanced Technology ISAT-1st Nanotechnology & its Related Sciences, Proceedings, p. 71, 2002.11.7, Tokyo, Japan.

14)E. Fujii, K. Kawabata, H. Yoshimatsu, A. Osaka, Y. Miura, "Development of calcia ceramics with high hydration resistance", The 19th Korea-Japan International Seminar on Ceramics, Proceedings P-5, pp. 480-483, 2002.11.21, Soul, Korea.

15)S. Takemoto, T. Yamamoto, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Blood compatibility of titanium oxide gels on titanium substrates", The 19th Korea-Japan International Seminar on Ceramics, Proceedings B-11, pp. 217-220, 2002.11.21, Soul, Korea.

16)K. Tsuru, S. Takemoto, T. Yamamoto, S. Hayakawa, A. Osaka, S. Takashima, "Blood copatibility of metal oxide layers on stainless-steel", Materials Research Society Fall Meeting, Abstract B9. p. 38, 2002.12.5, Boston, USA.

17)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "Blood compatibility of stainless-steel and titanium immobilized with alginic acid layers", Materials Research Society Fall Meeting, Avstract B9. 48, p. 38, 2002.12.5, Boston, USA.

18)A. Osaka, K. Tsuru, S. Hayakawa, "Synthesis of bioactive and porous organic-inorganic hybrids for biomedical applications", The 15th International Symposium on Ceramics in Medicine, Bioceramics15, 2002.12.5, Sydney, Australia.

19)K. Shibata, K. Tsuru, S. Hayakawa, A. Osaka, "Biomimetic apatite deposition on titanium substrates treated with low concentration H2O2 solutions", The 15th International Symposium on Ceramics in Medicine, Bioceramics15, pp. 55-58, 2002.12.5, Sydney, Australia.

20)S. Takashima, T. Yamamoto, K. Tsuru, S. Hayakawa, A. Osaka, "Deactivation of active oxygen speices due to metals and their blood compatibility", The 15th International Symposium on Ceramics in Medicine, Bioceramics15, pp. 105-107, 2002.12.5, Sydney, Australia.

21)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Cytocompatibility on silicone modified with organoalkoxysilane due to emulsion polymerization", The 15th International Symposium on Ceramics in Medicine, Bioceramics15, pp.687-690, 2002.12.5, Sydney, Australia.

22)J.-M. Wu, K. Tsuru, S. Hayakawa, A. Osaka, "Low temperature deposition of bioactive crystalline titania films: effects of tantalum", The 15th International Symposium on Ceramics in Medicine, Bioceramics15, pp. 533-536, 2002.12.5, Sydney, Australia.

23)F. Xiao, K. Tsuru, S. Hayakawa, A. Osaka, "Low temperature synthesis of bioactive titania thin films two-step treatment", The 15th International Symposium on Ceramics in Medicine, Bioceramics15, pp. 537-540, 2002.12.5, Sydney, Australia.

24)Y. Aburatani, T. Uchida, Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, "Response to osteoblastic cell of the organic-inorganic hybrids", The 15th International Symposium on Ceramics in Medicine, Bioceramics15, pp. 683-686, 2002.12.5, Sydney, Australia.