＜受賞＞
1)都留寛治，日本セラミックス協会進歩賞，"有機成分をハイブリッド化したセラミックス医用材料に関する研究”，2003年5月
1)都留寛治，早川聡，尾坂明義，高島征助，”血液適合性材料及びそれを用いた医療器具”，特開2003-284768，2003年10月7日公開
1)K. Tsuru, Y. Higashi, S. Hayakawa, A. Osaka, "Effects of organic molecules in the Kokubo’s simulated body fluid on apatite formation on bioactive glass and titanium", in Bioceramics: Materials and Applications IV, (Ceramic Transactions, Volume 147), American Ceramic Society, Westerville, Ohio, USA, pp. 103-110, 2003年4月
2)S. Hayakawa Y. Kusudo, S. Takemoto, K. Tsuru, A. Osaka, "Hydroxy-carbonate apatite, blood compatibility and adsorption of specific pathogenic proteins", in Bioceramics: Materials and Applications IV, (Ceramic Transactions, Volume 147), American Ceramic Society, Westerville, Ohio, USA, pp. 111-119, 2003年4月
1)X-X. Wang, W. Yan, S. Hayakawa, K. Tsuru, A. Osaka, "Apatite deposition on thermally and anodically oxidized titanium surfaces in a simulated body fluid", Biomaterials, 24[25], 4631-4637 (2003).
2)I. Yamaguchi, T. Kogure, M. Sakane, S. Tanaka, A. Osaka, J. Tanaka, "Microstructure analysis of calcium phosphate formed in tendon", Journal of Materials Science: Materials in Medicine, 14, 883-889 (2003).
3)J-M. Wu, F. Xiao, S. Hayakawa, K. Tsuru, S. Takemoto, A. Osaka, "Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution", Journal of Materials Science: Materials in Medicine, 14[12],1027-1032 (2003).
4)F. Xiao, K. Tsuru, S. Hayakawa, A. Osaka, "In vitro apatite deposition on titania film derived from chemical treatment of Ti substrates with an oxysulfate solution containing hydrogen peroxide at low temperature", Thin Solid Films, 441[1-2], 271-276 (2003).
5)Y. Aburatani, K. Tsuru, S. Hayakawa, A. Osaka, "Mechanical property and microstructure of bioactive organic-inorganic hybrids containing colloidal silica particles", Journal of the Ceramic Society of Japan, 111[4], 247-251 (2003).
6)Y. Aburatani, K. Tsuru, S. Hayakawa, A. Osaka, "Bioactivity of viscoelastic ormosil-type organic-inorganic hybrids containig colloidal silica particles", Journal of the Ceramic Society of Japan, 111[5], 318-322 (2003).
7)T. Asano, S. Takemoto, K. Tsuru, S. Hayakawa, A. Osaka, S. Takashima, "Sol-gel preparation of blood-compatible titania as an adsorbent of bilirubin", Journal of the Ceramic Society of Japan, 111[9], 645-650 (2003).
8)E. Fujii, K. Kawabata, H. Yoshimatsu, S. Hayakawa, K. Tsuru, A. Osaka, "Structure and biomineralization of calcium silicate glasses containing fluoride ions", Journal of the Ceramic Society of Japan, 111[10], 762-766 (2003).
9)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "Preparation of alginic acid layers on stainless-steel substrates for biomedical applications", Biomaterials, 24[17], 2889-2894 (2003).
10)T. Kim, M. Suzuki, C. Ohtsuki, K. Masuda, H. Tamai, E. Watanabe, A. Osaka, H. Moriya, "Enhancement of bone growth in titanium fiber mesh by surface modification with hydrogen peroxide solution containing tantalum chloride", Journal of Biomedical Materials Research Part B: Applied Biomaterials, 64B, 19-26 (2003).
11)J-M. Wu, S. Hayakawa, K. Tsuru, A. Osaka, "Early apatite deposition on titanium treated by hydrogen peroxide", Journal of Australian Ceramic Society, 39[1], 36-42 (2003).
12)I. Yamaguchi, S. Itoh, M. Suzuki, M. Sakane, A. Osaka, J. Tanaka, "The chitosan prepared from crab tendon I: the characterization and the mechanical properties", Biomaterials, 24[12], 2031-2036 (2003).
13)I. Yamaguchi, S. Itoh, M. Suzuki, A. Osaka, J. Tanaka, "The chitosan prepared from crab tendons: II. The chitosan/apatite composites and their application to nerve regeneration", Biomaterials, 24[19], 3285-3292 (2003).
14)I. Yamaguchi, S. Iizuka, A. Osaka, H. Monma, J. Tanaka, "The effect of citric acid addition on chitosan/hydroxyapatite composites", Colloids and Surfaces A: Physicochemical and Engineering Aspects, 214[1-3], 111-118 (2003).
15)A. Mori, I. Sakuramoto, E. Watanabe, K. Nagata, A. Osaka, K. Kuramoto, "Effects of manufacturing conditions on the oxidation resistance of directly molded UHMWPE", Journal of Japanese Society for Biomaterials, 21, 311-318 (2003).
16)森亜希子，富田直秀，金枝敏明，渡辺英一郎，永田員也，尾坂明義，蔵本孝一，"ビタミンE添加UHMWPE材料の疲労特性−人工関節におけるlift-offを考慮して−"，バイオマテリアル−生体材料−，21, 64-70 (2003).
17)A. Mori, C. Ohtsuki, A. Sugino, K. Kuramoto, T. Miyazaki, M. Tanihara, A. Osaka, "Bioactive PMMA-based bone cement modified with methacryloxypropyl-trimethoxysilane and calcium salts: Effects of calcium salts on apatite-forming ability", Journal of the Ceramic Society of Japan, 111, 738-742 (2003).
18)T. Yabuta, E.P. Bescger, J.D. Mackenzie, K. Tsuru, S. Hayakawa, C. Ohtsuki, A. Osaka, "Synthesis of PDMS-based porous materials for biomedical applications", Journal of Sol-Gel Science and Technology, 26[1-3], 1219-1222 (2003).
19)L. Ren, K. Tsuru, S. Hayakawa, A. Osaka, "In vitro evaluation of osteoblast response to Sol-Gel derived gelatin-siloxane hybrids", Journal of Sol-Gel Science and Technology, 26[1-3], 1137-1140 (2003).
1)S. Hayakawa, K. Shibata, K. Tsuru, A. Osaka, "Bioactive titania gel derived from combined chemical and thermal treatments of titanium", Ceramic Engineering and Science Proceedings, 27th International Cocoa Beach Conference on Advanced Ceramics and Composites: A , Vol. 24, Issue 3, ed. W. M. Kriven, H-T. Lin, pp. 227-232 (2003).
2)T. Ogawa, K. Tsuru, S. Hayakawa, S. Takashima, A. Osaka, "Effects of metals on generation and dismutation of active oxygen species in blood", Archives of BioCeramics Research, Vol. 3, ed. M. Okazaki, K. Ishikawa, K. Yamashita, Y. Doi, S. Ban, pp. 336-341 (2003).
3)S. Hayakawa, K. Tsuru, A. Osaka, "Platelet adhesion on titania film prepared from interaction of Ni-Ti alloy with hydrogen peroxide solution", in Bioceramics, Vol. 16, ed. M.A. Barbosa, F. J. Monteiro, R. Correia, B. Leon, Trans Tech Publications, pp. 865-868 (2003).
4)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, M. A. Lopes, J. D. Santos, M. H. Fernandes, "In vitro cytocompatibility of osteoblastic cells cultured on chitosan-organosiloxane hybrid membrane", in Bioceramics, Vol. 16, ed. M.A. Barbosa, F. J. Monteiro, R. Correia, B. Leon, Trans Tech Publications, pp. 857-860 (2003).
5)S. Takemoto, T. Yamamoto, K. Tsuru, S. Hayakawa, A. Osaka, "Platelet adhesion on metal oxide layers", in Bioceramics, Vol. 16, ed. M.A. Barbosa, F. J. Monteiro, R. Correia, B. Leon, Trans Tech Publications, pp. 853-856 (2003).
6)S. Kawasaki, K. Tsuru, S. Hayakawa, A. Osaka, "Control of morphology of titania film with high apatite-forming ability derived from chemical treatments of titanium with hydrogen peroxide", in Bioceramics, Vol. 16, ed. M.A. Barbosa, F. J. Monteiro, R. Correia, B. Leon, Trans Tech Publications, pp. 443-446 (2003).
7)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "Blood compatibility of stainless-steel and titanium immobilized with alginic acid layers", Materials Research Society Symposium Proceeding, Vol. 734, pp.333-338 (2003).
8)K. Tsuru, S. Takemoto, T. Yamamoto, S. Hayakawa, A. Osaka, S. Takashima, "Blood compatibility of metal oxide layers on stainless-steel", Materials Research Society Symposium Proceeding, Vol. 734, pp.327-332 (2003).
1)Y. Kuboki, R. Yoshimoto, N. Tanaka, H. Takita, K. Tsuru, A. Osaka, A. Yanagisawa, M. Kaneko, K. Nemoto, T. Miyata, "Geometry of artificial extracellular matrix: Creation of three-dimensional bonding between bone and titanium by the web of 50-microns titanium fibers", Bone, 32[5], pp. S194-S194, (2003). Meeting Abstract.
2)Y. Kuboki, R. Yoshimoto, N. Tanaka, H. Uramoto Y., Takita, K. Tsuru, A. Osaka, M. Kaneko, A. Yanagisawa, K. Nemoto, T. Miyata, "Web of fine titanium fibers created a three-dimensional bonding between bone and titanium by the geometry of artificial ECM", Journal of Dental Research, 82, Sp. Iss. B, pp. B277-B277, (2003). Meeting Abstract.
3)S. Hayakawa, A. Osaka, K. Shibata, K. Tsuru, "Bioactive titania gel-derived from combined chemical and thermal treatments of titanium", The 27th Annual Cocoa Beach Conference & Exposition on Advanced Ceramics & Composites, 2003.1.29-30, Cocoa Beach, U.S.A.
4)Y. Kusudo, K. Tsuru, S. Hayakawa, S. Takashima, A. Osaka, "Hydroxy-carbonate apatite: synthesis, blood compatibility and adsorption of specific pathogenic proteins", The ACerS 105th Annual Meeting and Exposition, Abstract AM-S2-29-2003, p. 10, 2003.4.28-29, Nashville, U.S.A.
5)Y. Higashi, K. Tsuru, S. Hayakawa, A. Osaka, "Effects of organic molecules in the Kokubo's simulated body fluid on apatite formation on bioactive glass and titanium substrates", The ACerS 105th Annual Meeting and Exposition, Abstract AM-S2-7-2003, 2003.4.28-29, Nashville, U.S.A.
6)T. Yabuta, K. Tsuru, S. Hayakawa, A. Osaka, "Synthesis of blood compatible PDMS-based organic-inorganic hybrid coatings", 12th International Workshop on Sol-Gel Science and Technology, Abstract 743, p. 240, 2003.8.24-29, Sydney, Australia.
7)A. Osaka, K. Tsuru, S. Hayakawa, "Synthesis of bioactive and porous organic-inorganic hybrids and their biomedical application", 12th International Workshop on Sol-Gel Science and Technology, Abstract I12, p. 58, 2003.8.24-29, Sydney, Australia.
8)K. Tsuru, Y. Shirosaki, S. Hayakawa, A. Osaka, "In vitro biological reactivity of chitosan-organosiloxane hybrid", European Congress and Exhibition on Advanced Materials and Processes (EUROMAT2003), Symposium C3, Session: Bio-Active and Bio-Hybrid materials, Programme p. 28, 2003.09.02, Switzerland, Lausanne.
9)E. Fujii, K. Kawabata, H. Yoshimatsu, K. Tsuru, S. Hayakawa, A. Osaka,
"Preparation and properties of hydroxyapatite powder with metal alkoxide",
The 5th International
Meeting of Pacific Rim Ceramic Societies, Abstract aa-P-03, p. 171, 2003.9.30,
Nagoya, Japan.
8)S. Hayakawa, K. Tsuru, Y. Higashi, A. Osaka, "Apatite formation on bioactive glass and titanium substrate in the Kokubo's simulated body fluid containing organic molecules", The 5th International Meeting of Pacific Rim Ceramic Societies, Abstract 11-O-05, p. 164, 2003.9.30, Nagoya, Japan.
9)K. Tsuru, T. Yamamoto, Y. Yamane, S. Hayakawa, A. Osaka, "Blood compatibility
of Sol-Gel derived metal oxide layers", The 5th International Meeting
of Pacific Rim Ceramic
Societies, Abstract 11-O-20, p. 168, 2003.10.1, Nagoya, Japan.
10)T. Yamamoto, A. Osaka, S. Hayakawa, K. Tsuru, S. Takashima, "Blood
compatibility of titanium oxide layer prepared by chemical and heat treatments",
The 5th International
Meeting of Pacific Rim Ceramic Societies, Abstract 11-P-21, p. 176, 2003.10.1,
Nagoya, Japan.
11)A. Osaka, S. Takemoto, K. Tsuru, S. Hayakawa, S. Takashima, "Blood-compatible titania and carbonate apatite for selective adsorption of protains", The 5th International Meeting of Pacific Rim Ceramic Societies, Abstract 11-I-05, p. 163, 2003.10.1, Nagoya, Japan.
12)A. Osaka, K. Tsuru, S. Hayakawa, "Porous organic - inorganic hybrids for tissue engineering application", The 8th IUMRS International Conference on Advanced Materials, C9-12-O11, 2003.10.12, Yokohama, Japan.
13)T. Yoshioka, K. Tsuru, S. Hayakawa, A. Osaka, "In vitro platelet adhesion and protein adsorption of biomedical implant modified with polysaccharide", The 8th IUMRS International Conference on Advanced Materials, C4-13-P06, 2003.10.13, Yokohama, Japan.
14)N. Azuma, T. Ikoma, A. Osaka, J. Tanaka, "Novel hydrogels of malic acid and zinc: Synthesis and characterization", The 8th IUMRS International Conference on Advanced Materials, C9-12-O13, 2003.10.13, Yokohama, Japan.
15)A. Osaka, T. Yoshioka, T. Yabuta, K. Tsuru, S. Hayakawa, "Anti-blood
clotting behavior of metal implants hybridized with organic or inorganic coating",
Composites at Lake
Louise 2003, 2003.10.22, Lake Louise, Canada.
16)S. Hayakawa, K. Tsuru, A. Osaka, "Platelet adhesion on titania film prepared from interaction of Ni-Ti alloy with hydrogen peroxide solution", The 16th International Symposium on Ceramics in Medicine, Bioceramics, Vol.16, 2003.11.08, Porto, Portugal.
17)S. Takemoto, T. Yamamoto, K. Tsuru, S. Hayakawa, A. Osaka, "Platelet adhesion on metal oxide layers", The 16th International Symposium on Ceramics in Medicine, Bioceramics, Vol.16, 2003.11.08, Porto, Portugal.
18)S. Kawasaki, K. Tsuru, S. Hayakawa, A. Osaka, "Control of morphology of titania film with high apatite-forming ability derived From chemical treatments of titanium with hydrogen peroxide", The 16th International Symposium on Ceramics in Medicine, Bioceramics, Vol.16, 2003.11.08, Porto, Portugal.
19)Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka, M.A. Lopes, J.D. Santos, M.H. Fernandes, "In vitro cytocompatibility of osteoblastic cells cultured on chitosan-organosiloxane hybrid membrane", The 16th International Symposium on Ceramics in Medicine, Bioceramics, Vol.16, 2003.11.08, Porto, Portugal.
20)T. Ogawa, K. Tsuru, S. Hayakawa, S. Takashima, A. Osaka, "Effect of metals on generation and dismutation of active oxygen species in blood", The 3nd Asian BioCeramics Symposium (ABC2003), Proc. pp. 336-341, 2003.11.20, Fukuoka, Japan.
21)Y. Liu , K. Tsuru, S. Hayakawa, A. Osaka, "Titanate nano-rods grown on titanium substrates", The 20th International Japan-Korea Seminar on Ceramics, pp. 299-302, 2003.11.20-22, Matsue, Japan.
22)N. Azuma, T. Ikoma, A. Osaka, J. Tanaka, "Novel malic acid-zinc hydrogels", The MRS International Conference fall meeting 2003, Abstract K7-22, p. 145, 2003.12.3, Boston, USA.
1)K. Tsuru, K. Shibata, T. Yamamoto, S. Hayakawa, A. Osaka, S. Takashima(Co-operative
Research Center), "Synthesis of titanium oxide layer with biocompatibility”,
第41回セラ
ミックス基礎科学討論会, 2003年1月22日-23日, 鹿児島市（ホテルウェルビューかごしま）
2) 楠戸ゆう子，都留寛治，早川聡，尾坂明義，高島征助, "炭酸含有ヒドロキシアパタイトの選択的タンパク質吸着 その2", 第41回セラミックス基礎科学討論会, 2003年1月22日-23日, 鹿児島市（ホテルウェルビューかごしま）
3) 都留寛治,早川聡, 尾坂明義, "金属酸化物の生体反応性", 日本セラミックス協会2003年年会サテライトプログラム第2回ベクトルセラミックス研究討論会講演, 2003年3月22日, 八王子市（東京都立大学）
4)都留寛治，山田彩，城崎由紀，早川聡，尾坂明義, "キトサン-オルガノシロキサン複合体のin vitro生体反応性", 日本セラミックス協会2003年年会, 2003年3月22日-24日, 八王子市（東京都立大学）
5) 早川聡，東義慶，都留寛治，柴田浩一，尾坂明義, "材料のアパタイト形成能に及ぼす模擬体液中の有機成分の影響（II）", 日本セラミックス協会2003年年会, 2003年3月22日-24日, 八王子市（東京都立大学）
6) 山根淑暢，都留寛治，早川聡，尾坂明義, "ゾル-ゲル法で作製した各種金属酸化物の血液適合性", 日本セラミックス協会支部連合学術講演会, 2003年9月5日, 大阪市（大阪大学産業科学研究所）
7)東紀史，生駒俊之，尾坂明義，田中順三，"低分子有機酸と亜鉛イオンを用いたハイドロゲルの合成とその特性", 第52回高分子討論会，講演番号IIY18，4021頁，2003年9月5日，山口市（山口大学）
8) 籔田武司，都留寛治，早川聡，尾坂明義, "TEOS-PDMS型ナノハイブリッド多孔体の合成と生体適合性", 第44回ガラスおよびフォトニクス材料討論会, 2003年11月21日, 京都市（京都大学化学研究所）
9)山根淑暢，都留寛治，早川聡，尾坂明義, "ゾル-ゲル法により作製した各種金属酸化物のin vitro血小板粘着性評価", 第7回生体関連セラミックス討論会, 講演番号I-19，19頁，2003年12月4日-5日, 文京区（東京医科歯科大学）
10)城崎由紀，都留寛治，早川聡，尾坂明義，M.A. Lopes，J.D. Santos，M.H. Fernandes, "キトサンーシリケート複合体の合成とin vitro細胞適合性評価", 第7回生体関連セラミックス討論会，講演番号I-23，23頁，2003年12月4日-5日，文京区（東京医科歯科大学）
11)大久保瑞樹，楠戸ゆう子，都留寛治，早川聡，尾坂明義，高島征助, "病因タンパク質吸着特性を有する炭酸含有アパタイトの合成", 第10回ヤングセラミスト・ミーティングin中四国, 講演番号B17，83-85頁，2003年12月6日, 松江市（島根大学）
12)吉岡朋彦，都留寛治，早川聡，尾坂明義, "アルギン酸を固定化した金属のタンパク質吸着特性", 第25回日本バイオマテリアル学会大会, 講演番号C-301，195頁，2003年12月16日-17日, 大阪市（大阪国際会議場）
13)城崎由紀，都留寛治，早川聡，尾坂明義，M.A. Lopes，J.D. Santos, M.H. Fernandes, "キトサン-シリケート複合体の微細構造と細胞適合性の評価", 第25回日本バイオマテリアル学会大会, 講演番号A-105，87頁，2003年12月16日-17日, 大阪市（大阪国際会議場）
13)東紀史，生駒俊之，尾坂明義，田中順三，"リンゴ酸・亜鉛ハイドロゲルへのヒアルロン酸添加効果"，第25回日本バイオマテリアル学会大会, 講演番号P-102，352頁，2003年12月16日-17日, 大阪市（大阪国際会議場）